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Physalin H from Solanum nigrum as an Hh signaling inhibitor blocks GLI1–DNA-complex formation
Hedgehog (Hh) signaling plays an important role in embryonic development, cell maintenance and cell proliferation. Moreover, Hh signaling contributes to the growth of cancer cells. Physalins are highly oxidized natural products with a complex structure. Physalins (1–7) were isolated from Solanum nig...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Beilstein-Institut
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896228/ https://ncbi.nlm.nih.gov/pubmed/24454566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.10 |
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