Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion

During tumor development, constant interplay occurs between tumor cells and surrounding stromal cells. We report evidence that gastrointestinal stromal tumor (GIST) cells invade the interstitial stroma through the release of the oncogenic protein tyrosine kinase (KIT)-containing exosomes, which trig...

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Detaylı Bibliyografya
Asıl Yazarlar: Atay, Safinur, Banskota, Samagya, Crow, Jennifer, Sethi, Geetika, Rink, Lori, Godwin, Andrew K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896203/
https://ncbi.nlm.nih.gov/pubmed/24379393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310501111
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