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Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion

During tumor development, constant interplay occurs between tumor cells and surrounding stromal cells. We report evidence that gastrointestinal stromal tumor (GIST) cells invade the interstitial stroma through the release of the oncogenic protein tyrosine kinase (KIT)-containing exosomes, which trig...

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Bibliografske podrobnosti
Main Authors: Atay, Safinur, Banskota, Samagya, Crow, Jennifer, Sethi, Geetika, Rink, Lori, Godwin, Andrew K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896203/
https://ncbi.nlm.nih.gov/pubmed/24379393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310501111
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