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Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion
During tumor development, constant interplay occurs between tumor cells and surrounding stromal cells. We report evidence that gastrointestinal stromal tumor (GIST) cells invade the interstitial stroma through the release of the oncogenic protein tyrosine kinase (KIT)-containing exosomes, which trig...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896203/ https://ncbi.nlm.nih.gov/pubmed/24379393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310501111 |
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