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Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion

During tumor development, constant interplay occurs between tumor cells and surrounding stromal cells. We report evidence that gastrointestinal stromal tumor (GIST) cells invade the interstitial stroma through the release of the oncogenic protein tyrosine kinase (KIT)-containing exosomes, which trig...

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Sonraí Bibleagrafaíochta
Main Authors: Atay, Safinur, Banskota, Samagya, Crow, Jennifer, Sethi, Geetika, Rink, Lori, Godwin, Andrew K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896203/
https://ncbi.nlm.nih.gov/pubmed/24379393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310501111
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