Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection

A unique avian-origin A/H7N9 influenza virus has so far caused 134 cases with 44 deaths. Probing the host factors contributing to disease severity, we found that lower levels of plasma inflammatory cytokines on hospital admission correlated with faster recovery in 18 patients with A/H7N9 influenza v...

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Hlavní autoři: Wang, Zhongfang, Zhang, Anli, Wan, Yanmin, Liu, Xinian, Qiu, Chao, Xi, Xiuhong, Ren, Yanqin, Wang, Jing, Dong, Yuan, Bao, Meijuan, Li, Liangzhu, Zhou, Mingzhe, Yuan, Songhua, Sun, Jun, Zhu, Zhaoqin, Chen, Liang, Li, Qingsheng, Zhang, Zhiyong, Zhang, Xiaoyan, Lu, Shuihua, Doherty, Peter C., Kedzierska, Katherine, Xu, Jianqing
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896201/
https://ncbi.nlm.nih.gov/pubmed/24367104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321748111
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