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Mutagenicity to Mammalian Cells of Epoxides and Other Derivatives of Polycyclic Hydrocarbons

The cytotoxicity and mutagenicity of several polycyclic hydrocarbons and their K-region derivatives were tested in a clone of Chinese hamster cells; the production of clones resistant to 8-azaguanine was used as the marker for mutagenesis. In the series related to benz(a)anthracene, the K-region epo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Huberman, Eliezer, Aspiras, Lourdes, Heidelberger, Charles, Grover, Philip L., Sims, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389620/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5289256/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.12.3195
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