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Hydrolysis of fMet-tRNA by Peptidyl Transferase

Escherichia coli and rabbit reticulocyte (f[(3)H]Met-tRNA·AUG·ribosome) intermediates undergo hydrolysis, with release of f[(3)H]methionine, upon addition of tRNA or CpCpA in the presence of acetone. This ribosomal catalyzed reaction has similar requirements, pH optimum, and antibiotic sensitivity t...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Caskey, C. T., Beaudet, A. L., Scolnick, E. M., Rosman, M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1971
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389613/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4943558/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.12.3163
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