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Genetics of Somatic Mammalian Cells: Lethal Antigens as Genetic Markers for Study of Human Linkage Groups

The antigen that causes killing of at least 98% of a human cell population treated with a 1% solution of a specific rabbit antiserum in the presence of complement is a sensitive genetic marker. The rapid loss of human chromosomes in human-Chinese hamster cell hybrids makes possible a convenient test...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Puck, Theodore T., Wuthier, Paul, Jones, Carol, Kao, Fa-Ten
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1971
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389599/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4332008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.12.3102
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