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Plasminogen initiates and potentiates the healing of acute and chronic tympanic membrane perforations in mice

BACKGROUND: Most tympanic membrane (TM) perforations heal spontaneously, but approximately 10-20% remain open as chronic TM perforations. Chronic perforations can lead to an impaired hearing ability and recurrent middle ear infections. Traditionally, these perforations must be surgically closed, whi...

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Autors principals: Shen, Yue, Guo, Yongzhi, Wilczynska, Malgorzata, Li, Jinan, Hellström, Sten, Ny, Tor
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895791/
https://ncbi.nlm.nih.gov/pubmed/24393366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-5
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