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Enzymatic Conversion of 5-Oxo-L-Proline (L-Pyrrolidone Carboxylate) to L-Glutamate Coupled with Cleavage of Adenosine Triphosphate to Adenosine Diphosphate, a Reaction in the γ-Glutamyl Cycle

A new enzyme, 5-oxoprolinase, was found in rat kidney and in several other tissues; it catalyzes the conversion of 5-oxo-L-proline (L-5-oxo-pyrrolidine-2-carboxylic acid, L-2-pyrrolidone-5-carboxylic acid, L-pyroglutamic acid) to L-glutamic acid, with concomitant stoichiometric cleavage of ATP to AD...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Werf, Paul Van Der, Orlowski, Marian, Meister, Alton
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1971
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389574/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5289242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.12.2982
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