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Improved reduced representation bisulfite sequencing for epigenomic profiling of clinical samples

BACKGROUND: DNA methylation plays crucial roles in epigenetic gene regulation in normal development and disease pathogenesis. Efficient and accurate quantification of DNA methylation at single base resolution can greatly advance the knowledge of disease mechanisms and be used to identify potential b...

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Détails bibliographiques
Auteurs principaux: Lee, Yew Kok, Jin, Shengnan, Duan, Shiwei, Lim, Yen Ching, Ng, Desmond PY, Lin, Xueqin Michelle, Yeo, George SH, Ding, Chunming
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895702/
https://ncbi.nlm.nih.gov/pubmed/24406024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1480-9222-16-1
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