Slow Joining of Newly Replicated DNA Chains in DNA Polymerase I-Deficient Escherichia coli Mutants

In Escherichia coli mutants deficient in DNA polymerase I, newly replicated short DNA is joined at about 10% of the rate in the wild-type strains. It is postulated that DNA polymerase I normally functions in filling gaps between the nascent short segments synthesized by the replication complex. Poss...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Okazaki, Reiji, Arisawa, Mikio, Sugino, Akio
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1971
Schlagworte:	Biological Sciences: Biochemistry
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4943548/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.12.2954
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