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Lessons from senescence: chromatin maintenance in non-proliferating cells
Cellular senescence is an irreversible proliferation arrest, thought to contribute to tumour suppression, proper wound healing and, perhaps, tissue and organismal aging. Two classical tumor suppressors, p53 and pRB, control cell cycle arrest associated with senescence. Profound molecular changes occ...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3895594/ https://ncbi.nlm.nih.gov/pubmed/21839870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2011.07.014 |
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