Evaluation of the Effect of miR-26b Up-Regulation on HbF Expression in Erythroleukemic K-562 Cell Line

BACKGROUND: The major hemoglobin in the fetus is hemoglobin F (HbF) (α2γ2), whereas in adult humans, hemoglobin A (α2β2) is predominately expressed. Several studies have indicated that expression of the HbF subunit γ-globin might be regulated post-transcriptionally. This could be done by small non-c...

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Bibliografski detalji
Glavni autori: Alijani, Sadegh, Alizadeh, Shaban, Kazemi, Ahmad, Khatib, Zahra Kashani, Soleimani, Masoud, Rezvani, Mohamadreza, Minayi, Neda, Karami, Farshid, Tayebi, Behnoosh
Format: Artigo
Jezik:Inglês
Izdano: Avicenna Research Institute 2014
Teme:
Short Communication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895580/
https://ncbi.nlm.nih.gov/pubmed/24523956
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