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Comparison of imatinib, nilotinib and silymarin in the treatment of carbon tetrachloride-induced hepatic oxidative stress, injury and fibrosis

Effective and well-tolerated anti-fibrotic drugs are currently lacking. Therefore, this study was carried out to investigate the potential anti-fibrotic effects of imatinib, nilotinib and silymarin on established hepatic fibrosis in the carbon tetrachloride (CCl(4)) rat model. Male Wistar rats recei...

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Detalhes bibliográficos
Main Authors: Shaker, Mohamed E., Zalata, Khaled R., Mehal, Wajahat Z., Shiha, Gamal E., Ibrahim, Tarek M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895503/
https://ncbi.nlm.nih.gov/pubmed/21316382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.02.004
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