Interleukin 7 receptor-deficient mice lack gammadelta T cells.

The interleukin 7 receptor (IL-7R) plays a crucial role in early B- and T-cell development. It consists of a unique a chain and a common gamma chain [IL-2 receptor gamma chain (IL-2Rgamma)]. Gene inactivation of IL-7, IL-7R, and IL-2Rgamma resulted in severe impairment of B and T lymphopoiesis in mi...

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Bibliographic Details
Main Authors: Maki, K, Sunaga, S, Komagata, Y, Kodaira, Y, Mabuchi, A, Karasuyama, H, Yokomuro, K, Miyazaki, J I, Ikuta, K
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC38955/
https://ncbi.nlm.nih.gov/pubmed/8692964
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