A study of human furin specificity using synthetic peptides derived from natural substrates, and effects of potassium ions

We explored furin substrate requirements in addition to the motif R-X-K/R-R using synthetic fluorescent resonance energy transfer (FRET) decapeptides. These decapeptides were derived from furin cleavage sites in viral coat glycoproteins and human and bacterial protein precursors. The hydrolysis by f...

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Detalhes bibliográficos
Main Authors: Izidoro, Mario A., Gouvea, Iuri E., Santos, Jorge A.N., Assis, Diego M., Oliveira, Vitor, Judice, Wagner A.S., Juliano, Maria A., Lindberg, Iris, Juliano, Luiz
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895411/
https://ncbi.nlm.nih.gov/pubmed/19477160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.05.013
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