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Heterodimer formation and activity in the human enzyme galactose-1-phosphate uridylyltransferase.

One of the fundamental questions concerning expression and function of dimeric enzymes involves the impact of naturally occurring mutations on subunit assembly and heterodimer activity. This question is of particular interest for the human enzyme galactose-l-phosphate uridylyl-transferase (GALT), im...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Elsevier, J P, Wells, L, Quimby, B B, Fridovich-Keil, J L
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38954/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692963/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7166
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