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The hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intake

The cannabinoid 1 receptor (CB(1)R) has a well-established role in appetite regulation. Central CB(1)R antagonists, notably rimonabant, induced weight loss and improved the metabolic profile in obese individuals, but were discontinued due to psychiatric side-effects. The CB(1)R is also expressed per...

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Detalhes bibliográficos
Main Authors: Cooper, Martin E, Regnell, Simon E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895344/
https://ncbi.nlm.nih.gov/pubmed/23452341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12102
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