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The hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intake
The cannabinoid 1 receptor (CB(1)R) has a well-established role in appetite regulation. Central CB(1)R antagonists, notably rimonabant, induced weight loss and improved the metabolic profile in obese individuals, but were discontinued due to psychiatric side-effects. The CB(1)R is also expressed per...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3895344/ https://ncbi.nlm.nih.gov/pubmed/23452341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12102 |
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