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Inactivation of D-Alanine Carboxypeptidase by Penicillins and Cephalosporins Is Not Lethal in Bacillus subtilis

The D-alanine carboxypeptidase of Bacillus subtilis is a particulate enzyme that is irreversibly inactivated by penicillins and cephalosporins. However, the lethal concentrations of these antibiotics are not the same as those that inhibit enzymatic activity in vitro. 6-Aminopenicillanic acid inactiv...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Blumberg, Peter M., Strominger, Jack L.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1971
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389532/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4330943/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.11.2814
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