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An unusual mechanism for EF-Tu activation during tmRNA-mediated ribosome rescue

In bacteria, ribosomes stalled on truncated mRNAs are rescued by transfer-messenger RNA (tmRNA) and its protein partner SmpB. Acting like tRNA, the aminoacyl-tmRNA/SmpB complex is delivered to the ribosomal A site by EF-Tu and accepts the transfer of the nascent polypeptide. Although SmpB binding wi...

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Autori principali: Miller, Mickey R., Buskirk, Allen R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895274/
https://ncbi.nlm.nih.gov/pubmed/24345396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.042226.113
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