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Increased Survival of Sickle-Cell Erythrocytes after Treatment In Vitro with Sodium Cyanate

Cyanate reacts with the amino-terminal valine residues of hemoglobin S and prevents the sickling in vitro of 50-80% of the erythrocytes from patients with sickle-cell disease. The purpose of the studies reported here was to determine whether this anti-sickling effect would increase the survival of c...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Gillette, Peter N., Manning, James M., Cerami, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389526/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5288258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.11.2791
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