Homotropic Cooperative Binding of the First Component of Guinea Pig Complement to Rabbit IgG-Erythrocyte Complexes: A Possible Allosteric Effect

Binding of the activated first component of guinea pig complement to immune complexes formed between dinitrophenylated erythrocytes and rabbit IgG antibody to 2,4-dinitrophenylhapten has been studied quantitatively. Cooperative binding was observed; it in volves no interactions between the domains o...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Thompson, James J., Hoffmann, Louis G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1971
Assuntos:	Biological Sciences: Immunology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5288251/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.11.2730
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