The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.

Human gene MAGE-1 encodes tumor-specific antigens that are recognized on melanoma cells by autologous cytolytic T lymphocytes. This gene is expressed in a significant proportion of tumors of various histological types, but not in normal tissues except male germ-line cells. We reported previously tha...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	De Smet, C, De Backer, O, Faraoni, I, Lurquin, C, Brasseur, F, Boon, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38951/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692960/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7149
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