Effect Modification of the Association of Cumulative Exposure and Cancer Risk by Intensity of Exposure and Time Since Exposure Cessation: A Flexible Method Applied to Cigarette Smoking and Lung Cancer in the SYNERGY Study

The indiscriminate use of the cumulative exposure metric (the product of intensity and duration of exposure) might bias reported associations between exposure to hazardous agents and cancer risk. To assess the independent effects of duration and intensity of exposure on cancer risk, we explored effe...

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Main Authors: Vlaanderen, Jelle, Portengen, Lützen, Schüz, Joachim, Olsson, Ann, Pesch, Beate, Kendzia, Benjamin, Stücker, Isabelle, Guida, Florence, Brüske, Irene, Wichmann, Heinz-Erich, Consonni, Dario, Landi, Maria Teresa, Caporaso, Neil, Siemiatycki, Jack, Merletti, Franco, Mirabelli, Dario, Richiardi, Lorenzo, Gustavsson, Per, Plato, Nils, Jöckel, Karl-Heinz, Ahrens, Wolfgang, Pohlabeln, Hermann, Tardón, Adonina, Zaridze, David, Field, John K., 't Mannetje, Andrea, Pearce, Neil, McLaughlin, John, Demers, Paul, Szeszenia-Dabrowska, Neonila, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Stanescu Dumitru, Rodica, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Boffetta, Paolo, Forastiere, Francesco, Bueno-de-Mesquita, Bas, Peters, Susan, Brüning, Thomas, Kromhout, Hans, Straif, Kurt, Vermeulen, Roel
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
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Original Contributions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895097/
https://ncbi.nlm.nih.gov/pubmed/24355332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwt273
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