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The Not4 E3 Ligase and CCR4 Deadenylase Play Distinct Roles in Protein Quality Control
Eukaryotic cells control their proteome by regulating protein production and protein clearance. Protein production is determined to a large extent by mRNA levels, whereas protein degradation depends mostly upon the proteasome. Dysfunction of the proteasome leads to the accumulation of non-functional...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3895043/ https://ncbi.nlm.nih.gov/pubmed/24465968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086218 |
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