Application of a Genetically Encoded Biosensor for Live Cell Imaging of L-Valine Production in Pyruvate Dehydrogenase Complex-Deficient Corynebacterium glutamicum Strains

The majority of biotechnologically relevant metabolites do not impart a conspicuous phenotype to the producing cell. Consequently, the analysis of microbial metabolite production is still dominated by bulk techniques, which may obscure significant variation at the single-cell level. In this study, w...

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Bibliographische Detailangaben
Hauptverfasser: Mustafi, Nurije, Grünberger, Alexander, Mahr, Regina, Helfrich, Stefan, Nöh, Katharina, Blombach, Bastian, Kohlheyer, Dietrich, Frunzke, Julia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895001/
https://ncbi.nlm.nih.gov/pubmed/24465669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085731
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