Canine Parvovirus VP2 Protein Expressed in Silkworm Pupae Self-Assembles into Virus-Like Particles with High Immunogenicity

The VP2 structural protein of parvovirus can produce virus-like particles (VLPs) by a self-assembly process in vitro, making VLPs attractive vaccine candidates. In this study, the VP2 protein of canine parvovirus (CPV) was expressed using a baculovirus expression system and assembled into parvovirus...

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Detalhes bibliográficos
Main Authors: Feng, Hao, Hu, Gui-qiu, Wang, Hua-lei, Liang, Meng, Liang, Hongru, Guo, He, Zhao, Pingsen, Yang, Yu-jiao, Zheng, Xue-xing, Zhang, Zhi-fang, Zhao, Yong-kun, Gao, Yu-wei, Yang, Song-tao, Xia, Xian-zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894932/
https://ncbi.nlm.nih.gov/pubmed/24465364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079575
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