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The In Vivo Response of Stem and Other Undifferentiated Spermatogonia to the Reversible Inhibition of GDNF Signaling in the Adult

Maintaining adequate numbers of spermatogonial stem cells is required for the production of the millions of sperm required for male fertility. To date, however, the mechanisms that regulate the size of this pool in the adult are poorly defined. Glial cell line-derived neurotrophic factor (GDNF) is r...

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Bibliografiska uppgifter
Huvudupphovsmän: Savitt, Joseph, Singh, Dolly, Zhang, Chao, Chen, Liang-chin, Folmer, Janet, Shokat, Kevan M., Wright, William W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894909/
https://ncbi.nlm.nih.gov/pubmed/22232066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1028
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