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Expression of Tyrosine Aminotransferase Activity in Somatic-Cell Heterokaryons: Evidence for Negative Control of Enzyme Expression

Cells of the tyrosine aminotransferase (EC 2.6.1.5)-inducible line, HTC, were fused with those of the BRL-62 line, which contain little or no enzyme and are unresponsive to the usual steroid inducers. Histochemical examination of the resulting heterokaryons within 24 hr of the fusion showed them to...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Thompson, E. Brad, Gelehrter, T. D.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1971
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4109409/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.10.2589
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