Mitigation of ROS Insults by Streptomyces Secondary Metabolites in Primary Cortical Neurons

[Image: see text] Oxidative stress is a common point in neurodegenerative diseases, widely connected with mitochondrial dysfunction. In this study, we screened seven natural products from Streptomyces sources against hydrogen peroxide insult in primary cortical neurons, an oxidative stress in vitro...

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Main Authors: Leirós, Marta, Alonso, Eva, Sanchez, Jon A., Rateb, Mostafa E., Ebel, Rainer, Houssen, Wael E., Jaspars, Marcel, Alfonso, Amparo, Botana, Luis M.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2013
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894724/
https://ncbi.nlm.nih.gov/pubmed/24219236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn4001878
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