Mitigation of ROS Insults by Streptomyces Secondary Metabolites in Primary Cortical Neurons

[Image: see text] Oxidative stress is a common point in neurodegenerative diseases, widely connected with mitochondrial dysfunction. In this study, we screened seven natural products from Streptomyces sources against hydrogen peroxide insult in primary cortical neurons, an oxidative stress in vitro...

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Main Authors: Leirós, Marta, Alonso, Eva, Sanchez, Jon A., Rateb, Mostafa E., Ebel, Rainer, Houssen, Wael E., Jaspars, Marcel, Alfonso, Amparo, Botana, Luis M.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2013
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894724/
https://ncbi.nlm.nih.gov/pubmed/24219236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn4001878
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