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Beta Thalassemia and Translation of Globin Messenger RNA

To define the quality and relative quantity of beta and alpha messenger RNA in human nonthalassemic and thalassemic reticulocytes, intact cells were incubated with [(35)S]methionine. The relative amounts of beta- and alpha-nascent chains on polysomes of different sizes were measured by tryptic diges...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Nathan, David G., Lodish, Harvey F., Kan, Yuet W., Housman, David
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1971
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389458/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5289885/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.10.2514
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