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The Isolation of Digoxin-Specific Antibody and Its Use in Reversing the Effects of Digoxin

Specific antibodies to digoxin were isolated from antisera of sheep immunized with a digoxin-human serum albumin conjugate. The antibody was purified by adsorption to an immunoadsorbent, synthesized by coupling a ouabain-ribonuclease conjugate to bromoacetyl-cellulose, followed by elution with 25 mM...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Curd, John, Smith, Thomas W., Jaton, Jean-Claude, Haber, Edgar
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1971
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389431/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5289875/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.10.2401
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