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Glycoprotein B (gB) vaccines adjuvanted with AS01 or AS02 protect female guinea pigs against cytomegalovirus (CMV) viremia and offspring mortality in a CMV-challenge model

The transmission of cytomegalovirus (CMV) from mother to fetus can give rise to severe neurodevelopment defects in newborns. One strategy to prevent these congenital defects is prophylactic vaccination in young women. A candidate vaccine antigen is glycoprotein B (gB). This antigen is abundant on th...

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Detalhes bibliográficos
Main Authors: Schleiss, Mark R., Choi, K. Yeon, Anderson, Jodi, Mash, Janine Gessner, Wettendorff, Martine, Mossman, Sally, Van Damme, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894257/
https://ncbi.nlm.nih.gov/pubmed/23867012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.07.010
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