Safety and Efficacy of Single Dose versus Multiple Doses of AmBisome® for Treatment of Visceral Leishmaniasis in Eastern Africa: A Randomised Trial

BACKGROUND: Anti-leishmanial drug regimens that include a single dose AmBisome® could be suitable for eastern African patients with symptomatic visceral leishmaniasis (VL) but the appropriate single dose is unknown. METHODOLOGY: A multi-centre, open-label, non-inferiority, randomized controlled tria...

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Hlavní autoři: Khalil, Eltahir A. G., Weldegebreal, Teklu, Younis, Brima M., Omollo, Raymond, Musa, Ahmed M., Hailu, Workagegnehu, Abuzaid, Abuzaid A., Dorlo, Thomas P. C., Hurissa, Zewdu, Yifru, Sisay, Haleke, William, Smith, Peter G., Ellis, Sally, Balasegaram, Manica, EL-Hassan, Ahmed M., Schoone, Gerard J., Wasunna, Monique, Kimutai, Robert, Edwards, Tansy, Hailu, Asrat
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894173/
https://ncbi.nlm.nih.gov/pubmed/24454970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002613
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