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Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?
DNA double-strand breaks (DSBs) are harmful lesions leading to genomic instability or diversity. Non-homologous end-joining (NHEJ) is a prominent DSB repair pathway, which has long been considered to be error-prone. However, recent data have pointed to the intrinsic precision of NHEJ. Three reasons...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894167/ https://ncbi.nlm.nih.gov/pubmed/24453986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004086 |
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