Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients

Oncolytic viruses, which preferentially lyse cancer cells and stimulate an antitumor immune response, represent a promising approach to the treatment of cancer. However, how they evade the antiviral immune response and their selective delivery to, and replication in, tumor over normal tissue has not...

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Bibliografische gegevens
Hoofdauteurs: Adair, Robert A., Roulstone, Victoria, Scott, Karen J., Morgan, Ruth, Nuovo, Gerard J., Fuller, Martin, Beirne, Deborah, West, Emma J., Jennings, Victoria A., Rose, Ailsa, Kyula, Joan, Fraser, Sheila, Dave, Rajiv, Anthoney, David A., Merrick, Alison, Prestwich, Robin, Aldouri, Amer, Donnelly, Oliver, Pandha, Hardev, Coffey, Matt, Selby, Peter, Vile, Richard, Toogood, Giles, Harrington, Kevin, Melcher, Alan A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893925/
https://ncbi.nlm.nih.gov/pubmed/22700953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003578
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