Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients

Oncolytic viruses, which preferentially lyse cancer cells and stimulate an antitumor immune response, represent a promising approach to the treatment of cancer. However, how they evade the antiviral immune response and their selective delivery to, and replication in, tumor over normal tissue has not...

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Main Authors: Adair, Robert A., Roulstone, Victoria, Scott, Karen J., Morgan, Ruth, Nuovo, Gerard J., Fuller, Martin, Beirne, Deborah, West, Emma J., Jennings, Victoria A., Rose, Ailsa, Kyula, Joan, Fraser, Sheila, Dave, Rajiv, Anthoney, David A., Merrick, Alison, Prestwich, Robin, Aldouri, Amer, Donnelly, Oliver, Pandha, Hardev, Coffey, Matt, Selby, Peter, Vile, Richard, Toogood, Giles, Harrington, Kevin, Melcher, Alan A.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893925/
https://ncbi.nlm.nih.gov/pubmed/22700953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003578
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