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Rotenone and paraquat perturb dopamine metabolism: a computational analysis of pesticide toxicity
Pesticides, such as rotenone and paraquat, are suspected in the pathogenesis of Parkinson’s disease (PD), whose hallmark is the progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Thus, compounds expected to play a role in the pathogenesis of PD will likely impact the fun...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893822/ https://ncbi.nlm.nih.gov/pubmed/24269752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2013.11.003 |
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