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d-Glucose and d-mannose-based metabolic probes. Part 3: Synthesis of specifically deuterated d-glucose, d-mannose, and 2-deoxy-d-glucose

Altered carbohydrate metabolism in cancer cells was first noted by Otto Warburg more than 80 years ago. Upregulation of genes controlling the glycolytic pathway under normoxia, known as the Warburg effect, clearly differentiates malignant from non-malignant cells. The resurgence of interest in cance...

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Detalhes bibliográficos
Main Authors: Fokt, Izabela, Skora, Stanislaw, Conrad, Charles, Madden, Timothy, Emmett, Mark, Priebe, Waldemar
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893820/
https://ncbi.nlm.nih.gov/pubmed/23376241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2012.11.021
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