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Negative learning bias is associated with risk aversion in a genetic animal model of depression

The lateral habenula (LHb) is activated by aversive stimuli and the omission of reward, inhibited by rewarding stimuli and is hyperactive in helpless rats—an animal model of depression. Here we test the hypothesis that congenital learned helpless (cLH) rats are more sensitive to decreases in reward...

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Bibliografiske detaljer
Main Authors: Shabel, Steven J., Murphy, Ryan T., Malinow, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893716/
https://ncbi.nlm.nih.gov/pubmed/24474914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2014.00001
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