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Pantetheine-Linked Peptide Intermediates in Gramicidin S and Tyrocidine Biosynthesis

To study the function of pantetheine in gramicidin S and tyrocidine biosynthesis, pepsin digests of the polymerizing enzymes, of which only the heavy ones contain pantetheine, were analyzed. The digests of gramicidin S enzymes charged with either [(14)C]proline or with D-phenylalanyl-[(14)C]proline,...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kleinkauf, Horst, Roskoski, Robert, Lipmann, Fritz
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1971
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389353/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4943784/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.9.2069
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