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Telomere shortening correlates to dysplasia but not to DNA aneuploidy in longstanding ulcerative colitis
BACKGROUND: Ulcerative colitis (UC) is a chronic, inflammatory bowel disease which may lead to dysplasia and adenocarcinoma in patients when long-lasting. Short telomeres have been reported in mucosal cells of UC patients. Telomeres are repetitive base sequences capping the ends of linear chromosome...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893461/ https://ncbi.nlm.nih.gov/pubmed/24405569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-14-8 |
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