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On the Theory of Ion Transport Across the Nerve Membrane, II. Potassium Ion Kinetics and Cooperativity (with x = 4)

We use a tetrahedral model of four interacting protein subunits to represent the K(+) channel or gate in the squid nerve membrane. The kinetic predictions, with varying degrees of cooperativity, are compared with experimental observations, especially those of Hodgkin and Huxley (J. Physiol. 117, 500...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Hill, Terrell L., Chen, Yi-Der
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1971
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389277/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5288756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.8.1711
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