Detection of TP53 R249 Mutation in Iranian Patients with Pancreatic Cancer

The TP53 gene encodes tumor protein p53 which play a major role in the etiology of pancreatic cancer. The important role of codon 249 of TP53 for binding of p53 to its sequence-specific consensus site in DNA has been revealed by crystallography's studies, and mutation at this codon was detected...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mohamadkhani, Ashraf, Naderi, Elnaz, Sharafkhah, Maryam, Fazli, Hamid Reza, Moradzadeh, Malihe, Pourshams, Akram
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi Publishing Corporation 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892507/
https://ncbi.nlm.nih.gov/pubmed/24489544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/738915
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