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CD19 as a therapeutic target in a spontaneous autoimmune polyneuropathy

Spontaneous autoimmune polyneuropathy (SAP) in B7-2 knock-out non-obese diabetic (NOD) mice is mediated by myelin protein zero (P0)-reactive T helper type 1 (Th1) cells. In this study, we investigated the role of B cells in SAP, focusing on CD19 as a potential therapeutic target. We found that P0-sp...

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Detalhes bibliográficos
Main Authors: Abraham, P M, Quan, S H, Dukala, D, Soliven, B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892409/
https://ncbi.nlm.nih.gov/pubmed/24116957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12215
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