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CD19 as a therapeutic target in a spontaneous autoimmune polyneuropathy

Spontaneous autoimmune polyneuropathy (SAP) in B7-2 knock-out non-obese diabetic (NOD) mice is mediated by myelin protein zero (P0)-reactive T helper type 1 (Th1) cells. In this study, we investigated the role of B cells in SAP, focusing on CD19 as a potential therapeutic target. We found that P0-sp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Abraham, P M, Quan, S H, Dukala, D, Soliven, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892409/
https://ncbi.nlm.nih.gov/pubmed/24116957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12215
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