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Mutations in the Drosophila ortholog of the vertebrate Golgi pH regulator (GPHR) protein disturb endoplasmic reticulum and Golgi organization and affect systemic growth

Sorting of secretory cargo and retrieval of components of the biosynthetic pathway occur in organelles such as the Golgi apparatus, the endoplasmic reticulum and the endosomes. In order to perform their functions in protein sorting, these organelles require a weakly acidified lumen. In vitro data ha...

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Sonraí Bibleagrafaíochta
Main Authors: Charroux, Bernard, Royet, Julien
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Company of Biologists 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892162/
https://ncbi.nlm.nih.gov/pubmed/24357227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20137187
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