Resiquimod and polyinosinic–polycytidylic acid formulation with aluminum hydroxide as an adjuvant for foot-and-mouth disease vaccine

BACKGROUND: Toll-like receptor (TLR) agonists reportedly have potent antiviral and antitumor activities and may be a new kind of adjuvant for enhancing immune efficacy. Resiquimod (R848) is an imidazoquinoline compound with potent antiviral activity and functions through the TLR7/TLR8 MyD88-dependen...

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Detalhes bibliográficos
Main Authors: Zhou, Chun-Xue, Li, Dong, Chen, Ying-Li, Lu, Zeng-Jun, Sun, Pu, Cao, Yi-Mei, Bao, Hui-Fang, Fu, Yuan-Fang, Li, Ping-Hua, Bai, Xing-Wen, Xie, Bao-Xia, Liu, Zai-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892093/
https://ncbi.nlm.nih.gov/pubmed/24386990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-10-2
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