Phosphorylation of Ser1166 on GluN2B by PKA Is Critical to Synaptic NMDA Receptor Function and Ca(2+) Signaling in Spines

The NMDA-type glutamate receptor (NMDAR) is essential for synaptogenesis, synaptic plasticity, and higher cognitive function. Emerging evidence indicates that NMDAR Ca(2+) permeability is under the control of cAMP/protein kinase A (PKA) signaling. Whereas the functional impact of PKA on NMDAR-depend...

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Главные авторы: Murphy, Jessica A., Stein, Ivar S., Lau, C. Geoffrey, Peixoto, Rui T., Aman, Teresa K., Kaneko, Naoki, Aromolaran, Kelly, Saulnier, Jessica L., Popescu, Gabriela K., Sabatini, Bernardo L., Hell, Johannes W., Zukin, R. Suzanne
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2014
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891964/
https://ncbi.nlm.nih.gov/pubmed/24431445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4538-13.2014
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