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Restoration of Contact-Inhibited Growth to Transformed Cells by Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate

Spontaneously transformed and virally-transformed cells are restored to contact-inhibited growth by the addition of dibutyryl cyclic AMP to the nutrient medium. Theophylline, an inhibitor of the phosphodiesterase that degrades cyclic nucleotides, must also be present for maximal effect. Once the tra...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Sheppard, J. R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1971
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389180/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4331087/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.6.1316
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